DHEA-Sulfate (DHEA-S)

CPT: 82627
Hormones

What This Test Measures

Adrenal androgen precursor; reflects adrenal function; often tested in adrenal fatigue workup.

Preparation

No fasting required
Morning draw preferred as DHEA follows a diurnal pattern. No fasting required. Avoid high-dose DHEA supplements for 48 hours before testing.
💬 Patient Community Notes

TIMING: Draw in the morning — DHEA-S has mild diurnal variation (higher AM). Avoid testing when acutely stressed if possible, as chronic stress depletes DHEA. The functional medicine community aims for upper-normal range for age, roughly 200–350 µg/dL for women and 350–500 µg/dL for men, or levels optimal in one’s 20s. Standard medicine rarely addresses low-normal DHEA-S. These notes reflect common practices in functional medicine communities.

Reflects common practices in thyroid, BHRT, and functional medicine communities. This may differ from standard clinical guidelines. Not medical advice — always discuss with your provider.

General guidelines only. Requirements vary by lab and individual. Confirm with your provider before adjusting any medications.

Turnaround Time

Varies by lab

Clinical Notes

Most stable form of DHEA; does not require timed draw

ICD-10 Codes

Common diagnosis codes associated with this test. Codes are assigned by your provider.

E27.49Other adrenocortical insufficiency
E28.39Other ovarian dysfunction
R53.83Other fatigue

Self-Pay Pricing

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Life Extension

Uses Labcorp network; known for supplement company; competitive lab test pricing

$45.00Order
DirectLabs

Uses Quest Diagnostics network; good panel pricing; established DTC provider

$45.00Order
Personalabs

Uses Quest and Labcorp; no hidden draw or facility fees; moderate pricing

$49.00Order
Ulta Lab Tests

Uses Quest Diagnostics network; generally lowest DTC prices; not available in NY, NJ, RI

$49.00Order
Walk-In Lab

Uses both Quest and Labcorp networks; competitive pricing; broad test selection

$59.00Order
Request A Test

Uses Quest and Labcorp networks; offers both individual tests and discounted panels

$59.00Order
Labcorp OnDemand

Labcorp consumer-direct platform; 2,000+ locations; results in 1-3 days

$59.00Order
Private MD Labs

Primarily uses Labcorp network; popular for hormone panels; higher individual test prices

$65.00Order
QuestDirect

Quest Diagnostics consumer-direct platform; results in 1-2 days; 2,100+ locations nationwide

$69.00Order
HealthLabs.com

Uses Quest and Labcorp; strong panel bundling; results in 1-3 days

$169.00Order

Lab Codes

Proprietary codes used by each lab for this test.

American Esoteric Labs
E485(order_code)
ARUP Laboratories
0070051(order_code)
BioReference Laboratories
0406-9(order_code)
Cleveland Clinic
DHEAS(mnemonic)
Clinical Labs of Hawaii
8018(order_code)
CPL
4225(order_code)
Geisinger Medical Labs
LAB2180(lab_id)
Interpath Laboratory
2214(order_code)
LabCorp
004020(order_code)
LabCorp
500161(order_code)
Mayo Clinic Labs
DHEA/9429(order_code)
Northwell Health Labs
5900535(order_code)
NYU Langone Health
LAB524(order_code)
Quest Diagnostics
402(order_code)
Stanford Health Care
DHS(order_code)

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For informational purposes only

This page is for educational and research purposes only and does not constitute medical advice, diagnosis, or treatment recommendations. ICD-10 and CPT codes are assigned by your healthcare provider. Always consult a qualified healthcare provider before ordering any lab test or making decisions about your health.