hs-CRP (High Sensitivity CRP)
What This Test Measures
High-sensitivity CRP measuring very low inflammation levels; strong cardiovascular risk predictor.
Preparation
TIMING: Avoid testing within 48–72 hours of intense exercise (weight training, long runs), acute illness, injury, dental work, or infection — all dramatically elevate CRP and mask your true baseline. The functional medicine community recommends testing when you're feeling well and haven't recently been sick or had a hard workout. If you get a high result unexpectedly, retest in 2–3 weeks. Optimal hs-CRP is below 0.5 mg/L per functional practitioners (vs. the standard <3.0 mg/L cardiac risk cutoff). CRP above 1.0 is considered evidence of chronic low-grade inflammation. No fasting required, but some practitioners prefer fasting for consistency.
Reflects common practices in thyroid, BHRT, and functional medicine communities. This may differ from standard clinical guidelines. Not medical advice — always discuss with your provider.
General guidelines only. Requirements vary by lab and individual. Confirm with your provider before adjusting any medications.
Turnaround Time
Varies by lab
Clinical Notes
Reynolds Risk Score incorporates hs-CRP; <1 mg/L low risk; 1-3 average; >3 high risk
ICD-10 Codes
Common diagnosis codes associated with this test. Codes are assigned by your provider.
Self-Pay Pricing
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Uses Quest Diagnostics network; generally lowest DTC prices; not available in NY, NJ, RI
Uses both Quest and Labcorp networks; competitive pricing; broad test selection
Uses Quest Diagnostics network; good panel pricing; established DTC provider
Uses Labcorp network; known for supplement company; competitive lab test pricing
Uses Quest and Labcorp; no hidden draw or facility fees; moderate pricing
Uses Quest and Labcorp; strong panel bundling; results in 1-3 days
Uses Quest and Labcorp networks; offers both individual tests and discounted panels
Labcorp consumer-direct platform; 2,000+ locations; results in 1-3 days
Quest Diagnostics consumer-direct platform; results in 1-2 days; 2,100+ locations nationwide
Primarily uses Labcorp network; popular for hormone panels; higher individual test prices
At-home self-collection. Finger prick or swab — no lab visit required. Results via secure portal within 10 business days.
Lab Codes
Proprietary codes used by each lab for this test.
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For informational purposes only
This page is for educational and research purposes only and does not constitute medical advice, diagnosis, or treatment recommendations. ICD-10 and CPT codes are assigned by your healthcare provider. Always consult a qualified healthcare provider before ordering any lab test or making decisions about your health.